论文部分内容阅读
目的探讨6 min步行训练对不同程度的慢性心力衰竭(CHF)患者血脑钠肽(BNP)及心功能的影响。方法将63例心功能II-III级的慢性心衰患者按分层抽样法随机分为训练组和(n=33)对照组(n=30),在入院后24 h内行BNP、左心室射血分数(LVEF)及6 min步行距离测定,然后两组均行常规抗心衰药物治疗,但训练组每天2次6 min步行运动训练,8周后重复检测上述指标。结果两组在治疗后BNP水平下降,训练组更为显著,心功能II级(352.35±81.45)pg/ml,心功能III级(523.65±98.45)pg/ml;治疗前后两组左心室射血分数(LVEF)均有明显上升,训练组更为显著;及6 min步行距离测定训练组步行距离在治疗8周后比对照组延长更为显著。结论血脑那肽水平随着心功能改善明显下降;6 min步行运动训练可显著改善慢性心衰患者的心脏功能,血脑钠肽下降,左室射血分数升高。
Objective To investigate the effects of 6-minute walking training on blood brain natriuretic peptide (BNP) and cardiac function in patients with chronic heart failure (CHF). Methods Sixty-three patients with chronic heart failure with grade II-III heart failure were randomly divided into training group and control group (n = 30) by stratified sampling method. BNP, left ventricular ejection (LVEF) and 6-min walk distance, and then both groups were treated with conventional anti-heart failure drugs. However, the training group received 6-minute walking training twice daily and the above indexes were repeated 8 weeks later. Results The levels of BNP in the two groups decreased after training, and the training group was more significant. The level of BNP was (352.35 ± 81.45) pg / ml and the level of heart function was (523.65 ± 98.45) pg / ml. Score (LVEF) were significantly increased, the training group is more significant; and 6 min walking distance measured training group walking distance in the treatment of 8 weeks after the extension of the more significant than the control group. Conclusion The level of blood brain natriuretic peptide decreased significantly with the improvement of cardiac function. The 6-minute walking training significantly improved the cardiac function, blood brain natriuretic peptide and left ventricular ejection fraction in patients with chronic heart failure.