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目的:研究分析C-反应蛋白(CRP)和降钙素原(PCT)应用于重症肺炎诊断的效果和价值,以有效指导临床实践和研究。方法:本次研究中共入选研究对象74例,均为2011年6月-2014年6月期间在祥云县人民医院接受治疗的肺炎患者。根据患者的疾病类型分组,细菌性肺炎组40例(观察A组)、支原体肺炎组34例(观察B组),选取同期在本院接受检查的无感染健康者40例为对照组。比较各组对象的白细胞计数(WBC)、CRP、PCT的检验结果。结果:经比较观察A组患者的WBC、CRP、PCT检验结果均明显高于对照组,B组患者的PCT和CRP水平高于对照组,差异具有统计学意义(P<0.05)。A组患者的PCT的血清水平高于其他组,阳性率为94.2%,A组、B组患者的阳性率依次为97.1%、92.8%。结论:重症肺炎患者的早期诊断中,CRP和PCT的阳性检出率较高,是其临床诊断的重要指标,其中二者水平同时增高可诊断为细菌性肺炎,二者均不上升即可确诊为病毒性肺炎,CRP水平单一升高确诊为支原体肺炎。
Objective: To study the effect and value of C-reactive protein (CRP) and procalcitonin (PCT) in the diagnosis of severe pneumonia so as to effectively guide the clinical practice and research. Methods: A total of 74 patients were enrolled in this study. All of them were pneumonia patients who were treated in Xiangyun People’s Hospital from June 2011 to June 2014. According to the types of patients, 40 cases of bacterial pneumonia group (observation group A), 34 cases of mycoplasma pneumonia group (observation group B), and 40 cases of non-infected healthy people who were checked in our hospital during the same period were selected as the control group. The white blood cell count (WBC), CRP and PCT test results of each group were compared. Results: The WBC, CRP and PCT test results in group A were significantly higher than those in control group. The PCT and CRP levels in group B were significantly higher than those in control group (P <0.05). The serum levels of PCT in group A were higher than those in other groups, the positive rate was 94.2%. The positive rates of group A and group B were 97.1% and 92.8% respectively. Conclusion: In the early diagnosis of severe pneumonia, the positive detection rate of CRP and PCT is high, which is an important index of clinical diagnosis, and both of them can be diagnosed as bacterial pneumonia at the same time, both of which can be diagnosed For viral pneumonia, a single elevated CRP level was confirmed as mycoplasma pneumonia.