论文部分内容阅读
应用放射免疫法测定了20例手术治疗子宫肌瘤患者的外周血和子宫静脉血血清雌二醇（E2）、孕酮（P）、泌乳素（PRL）、睾酮（T）的浓度。结果，E2处于低水平状素，但子宫血明显高于外周血，差异具有显著性。PRL在子宫静脉血中水平明显高于外周血（P＜0.05），P处于高水平状态，T无改变。提示：子宫肌瘤的发生、发展与雌激素、PRL在子宫局部的高浓度有密切关系。高孕激素水平在子宫肌瘤生长、发展中可能起协同作用。为研究药物治疗子宫肌瘤提出了依据。
Serum estradiol (E2), progesterone (P), prolactin (PRL) and testosterone (T) concentrations were measured in 20 patients with uterine fibroids by radioimmunoassay. As a result, E2 was at a low level of hormone, but the uterine blood was significantly higher than the peripheral blood, the difference was significant. The level of PRL in uterine vein blood was significantly higher than that in peripheral blood (P <0.05), P was in a high level and T was unchanged. Tip: The occurrence and development of uterine fibroids and estrogen, PRL in the uterus at high concentrations are closely related. High progesterone levels in uterine fibroids growth and development may play a synergistic effect. The basis for the study of drug treatment of uterine fibroids.