论文部分内容阅读
目的:观察清肺解毒汤联合盐酸氨溴索片治疗支气管扩张的临床疗效.方法:选取本院呼吸科收治的97例的支气管扩张症患者,随机分为2组,对照组47例,观察组50例.对照组患者给予盐酸氨溴索片联合硫酸沙丁胺醇气雾剂治疗,以1月为1个疗程,连续服用6疗程.观察组患者采用清肺解毒汤联合盐酸氨溴索片治疗,1月为1个疗程,连续服用6疗程.比较治疗前后2组患者肺功能指标、血气分析指标、24小时痰总量、6个月内急性加重次数、生活质量评分及临床疗效.结果:治疗后观察组患者的各项肺功能指标显著较对照组患者高(JP<0.05);2组Pa02、Sa02及PaOJFi02均较治疗前的水平显著升高(P<0.05),PaCO2较治疗前的水平显著降低(P<0.05),并且观察组较对照组的变化幅度更为明显(P<0.05);2组患者治疗后的24小时痰总量、6个月内的急性加重次数均显著降低(P<0.05);并且治疗后观察组的24小时痰总量明显较对照组更低(P<0.05),急性加重次数明显少于对照组(P<0.05).观察组患者治疗后的BODE指数改善情况、临床疗效均明显优于对照组(P<0.05).结论:清肺解毒汤联合盐酸氨溴索片治疗支气管扩张症具有良好的临床疗效,值得临床推广.“,”Objective:To observe the clinical efficacy of Qingfei Jiedu Decoction combined with Ambroxol Hydrochloride Tablets in the treatment of bronchiectasis.Methods:97cases of bronchiectasis patients in our department of respiration were randomly divided into 2groups,47cases in the controlled group,50cases in the observation group.The patients in the controlled group were treated with Ambroxol Hydrochloride Tablets combined with Salbutamol Aerosol,and 1 courses were taken in January.6courses were taken continuously.Patients in the observation group were treated with Qingfei Jiedu Decoction combined with Ambroxol Hydrochloride Tablets,and 1 courses were taken in January.6courses were taken continuously.The lung function index,blood gas analysis index,total sputum volume of 24hours,the number of exacerbations in 6months,the quality of life score and the clinical efficacy were compared between the 2groups before and after treatment.Results:After treatment,the observation group of patients with the lung function index was significantly higher in patients (P<0.05);2groups of PaO2,SaO2 and PaO2/Fi02 were significantly higher than before treatment (P<0.05),PaCO2 was significantly lower than before treatment (P<0.05),and the observation group was more obviously than the controlled group (P<0.05),the 2group patients after 24hours of total sputum within 6months,the times of acute exacerbation were significantly decreased (P<0.05);and 24hours after treatment in the observation group,sputum volume was significantly lower than the controlled group (P<0.05),acute exacerbation the number was significantly less than the controlled group (P<0.05).The improvement of BODE index and clinical efficacy in the observation group were better than those in the controlled group (P<0.05).Conclusion:Qingfei Jiedu Decoction combined with Ambroxol Hydrochloride Tablets in the treatment of bronchiectasis has good clinical efficacy and is worthy of clinical promotion.