目的观察奥美拉唑、阿莫西林、克拉霉素三联疗法治疗幽门螺旋杆菌阳性消化性溃疡的疗效。方法将30例消化临溃疡患者给予奥美拉唑、阿莫西林、克拉霉素治疗。结果十二指肠溃疡总有效率为95%;胃溃疡总有效率71%;复合性溃疡总有效率为70%。30例消化临溃疡总有效率为87%。结论奥美拉唑、阿莫西林、克拉霉素三联疗法治疗幽门螺杆菌阳性消化临溃疡有较好疗法。 Objective To observe the curative effect of omeprazole, amoxicillin and clarithromycin triple therapy on Helicobacter pylori positive peptic ulcer. Methods 30 cases of digestive ulcer patients were given omeprazole, amoxicillin, clarithromycin treatment. Results The total effective rate of duodenal ulcer was 95%. The total effective rate of gastric ulcer was 71%. The total effective rate of composite ulcer was 70%. 30 cases of digestive ulcer the total effective rate was 87%. Conclusion Omeprazole, amoxicillin, clarithromycin triple therapy for Helicobacter pylori positive digestive ulcer have a better therapy.