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目的 :本文主要观察溶栓灌注对QT间期及其离散度 (QTdispersion ,QTd)的影响。 方法 :测定 37例心肌梗死 ,患者的QT >440ms及QTd >5 0ms的患者比例分别为 41%及 5 7%。用尿激酶 37例 ,剂量 10 0万～ 15 0万u ,溶栓后再通 17例 ,未通 2 0例。结果 :37例溶栓后 2周再通组QTmax(36 1± 2 8、417± 32 ,P <0 0 5 )显著较未通组小 ,QTd为 5 1± 18、72± 32 ,与未通组有较显著差异 (P <0 0 5 )。结论 :成功的溶栓治疗主要是通过对复极的影响来缩短QT间期及降低QTd。提示QTd可作为判断预后的独立参数
Objective: This article mainly observe the impact of thrombolysis on QT interval and its dispersion (QTdispersion, QTd). Methods: Totally 37 patients with myocardial infarction were enrolled. The patients with QT> 440ms and QTd> 5 0ms were 41% and 57% respectively. With urokinase in 37 cases, the dose of 10 million to 15 million u, after thrombolysis through 17 cases, failed 20 cases. Results: The QTmax (36 1 ± 2 8,417 ± 32, P <0 05) of the 37 reoperation groups after 2 weeks of thrombolysis was significantly smaller than that of the unreceded group and the QTd was 51 ± 18 and 72 ± 32, There was a significant difference (P <0 05). Conclusion: Successful thrombolytic therapy is mainly through the impact of repolarization to shorten the QT interval and reduce QTd. Tip QTd can be used as an independent parameter to determine the prognosis