论文部分内容阅读
应用免疫组化(PAP)染色法,对101例乳腺癌雌激素受体(ER)及孕酮受体(PR)进行标记。检测结果:ER 阳性49例(48.5%);PR 阳性37例(36.6%)。癌细胞分化程度与ER 及PR 阳性率呈正相关(P<0.01);乳腺癌周淋巴细胞浸润程度、腋淋巴结转移、病人的年龄、病程长短、原发肿块大小及临床分期与ER、PR 无明显关系(P>0.05)。提示测定ER 及PR,对乳腺癌的分化程度及临床是否选择内分泌治疗有一定的意义。
Immunohistochemical (PAP) staining was used to detect the expression of estrogen receptor (ER) and progesterone receptor (PR) in 101 cases of breast cancer. The test results: ER positive in 49 cases (48.5%); PR positive in 37 cases (36.6%). There was a positive correlation between the degree of differentiation of cancer cells and the positive rate of ER and PR (P <0.01). The degree of lymphocytic infiltration, axillary lymph node metastasis, patient’s age, duration of disease, size of primary tumor and clinical stage of breast cancer were not significantly different from ER and PR Relationship (P> 0.05). Prompt determination of ER and PR, the degree of differentiation of breast cancer and the clinical choice of endocrine therapy has some significance.