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Killer cell immunoglobulin-like receptors(KIRs)which are mainly expressed on natural killer(NK)cells are implicated in many virus infections.However,it is unclear whether or not KIRs are associated with susceptibility to Epstein-Barr virus(EBV)infection related diseases.Therefore,the purpose of our study was to investigate possible correlation between polymorphisms of KIR genes and infectious mononucleosis(IM)/EBV-associated hemophagocytic lymphohistiocytosis(EBV-HLH).
Killer cell immunoglobulin-like receptors (KIRs) which are mainly expressed on natural killer (NK) cells are implicated in many virus infections. Despite, it is unclear whether or not KIRs are associated with susceptibility to Epstein-Barr virus (EBV) infection related the purpose of our study was to investigate possible responsibility between polymorphisms of KIR genes and infectious mononucleosis (IM) / EBV-associated hemophagocytic lymphohistiocytosis (EBV-HLH).