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目的:研究毒性中药的毒理作用及炮制原理分析。方法:择于2014年2月至2015年3月于我院运用临床运用的毒性中药及中药炮制成品(即如饮片等等)的治疗案例各62例,即分为实验组(运用中药炮制成品)与对照组(直接使用微量毒性中药),所有治疗病患均签署手术同意书,分析所有案例出现不良反应情况,计算不良反应率。最后探讨毒性中药降低毒性,提升药性的有效炮制方法。结果:根据本次研究结果显示,在不良反应情况对比方面,研究组不良反应发生率为3.22%;而对照组不良反应发生率为35.48%,以上组间数据对比存在显著差异,符合统计学意义(P<0.05)。结论:在一般毒性中药药性过烈,毒性过强,临床直接运用会导致病患出现严重不良反应,而通过科学的炮制可以最大程度降低药物的毒性,发挥最大药效。
Objective: To study the toxicological effects of toxic traditional Chinese medicine and the principle of processing. Methods: Totally 62 cases of the treated cases of toxic traditional Chinese medicine and finished Chinese medicine products (ie, decoction pieces etc.) were randomly divided into experimental group (using finished products of Chinese traditional medicine ) And control group (direct use of trace toxic traditional Chinese medicine), all patients were treated for surgical consent were signed, analysis of adverse reactions in all cases, calculate the adverse reaction rate. Finally, to explore the toxicity of traditional Chinese medicine to reduce toxicity and improve drug-effective processing methods. Results: According to the results of this study, adverse reactions in the study group, the incidence of adverse reactions was 3.22%; while the incidence of adverse reactions in the control group was 35.48%, the data between the above groups were significantly different, in line with statistical significance (P <0.05). Conclusion: In the general toxicity of traditional Chinese medicine is too aggressive, toxicity is too strong, direct clinical use will lead to serious adverse reactions in patients, and through scientific processing can minimize the toxicity of drugs to maximize their efficacy.