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Objective:To evaluate the predictive value of electrocardiographic S1Q(Ⅲ)T(Ⅲ)pattern in patients with acute pulmonary embolism.Method:ECG was analyzed retrospectively in 102 patients with acute pulmonary embolism confirmed by spiral CT scan and Compared the clinical data between S1Q(Ⅲ)T(Ⅲ)positive and negative getup.Result:In 102 patients 29 cases have positive S1Q(Ⅲ)T(Ⅲ)positive rate was 28.4%.In S1Q(Ⅲ)T(Ⅲ)positive group and S1Q(Ⅲ)T(Ⅲ)negative group,41.4%vs 69.9%have vulnerable diagnosis before admitted,respectively (P<0.05),as well as the massive PE 48.3%vs 23.3%(P<0.05),mortality rate 24.1%vs 10.9(P<0.05),bilateral PE 86.3%vs 65.8%(P<0.05)and right side PE 10.3%vs 31.5%(P<0.05).Conclusion:positive Electrocardiographic S1Q(Ⅲ)T(Ⅲ)could not be served as the basic diagnosis criteria for acute PE.positive S1Q(Ⅲ)T(Ⅲ)ECG could decrease the misdiagnosis of acute PE,indicate higher possibility of bilateral and massive acute PE.