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目的:探讨恶性肿瘤血浆纤维蛋白原(FIB)检测的临床意义。方法:选择住院的良、恶性肿瘤患者和正常对照组,采用全自动分析仪ACL200测定FIB。结果:良性肿瘤组与正常对照组FIB水平比较,差异无统计学意义(P>0.05),恶性肿瘤组与正常对照组、良性肿瘤组相比较FIB水平升高,差异均有统计学意义(P<0.01)。结论:检测FIB水平对于辅助诊断良、恶性肿瘤有一定的临床意义,对于无其他原因可解释的高纤维蛋白原血症,应警惕恶性肿瘤的可能。
Objective: To investigate the clinical significance of detecting plasma fibrinogen (FIB) in malignant tumor. Methods: The hospitalized patients with benign and malignant tumors and normal control group were selected, and the FIB was measured by automatic analyzer ACL200. Results: There was no significant difference in FIB level between benign tumor group and normal control group (P> 0.05). The FIB level of malignant tumor group was significantly higher than that of normal control group and benign tumor group (P <0.01). Conclusion: The detection of FIB level has some clinical significance for the diagnosis of benign and malignant tumors. For the high fibrinogenmia which can be explained without other reasons, the possibility of malignant tumors should be warned.