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本文综述了睫状神经营养因子(CNTF)受体各个亚基的分子和基因结构,对CNTF受体信号转导机理进行概括,并探讨了CNTF与造血生长因子在信号转导上的相似性,以阐明CNTF对于造血系统的可能作用。
This review summarizes the molecular and gene structure of each subunit of ciliary neurotrophic factor (CNTF) receptor, summarizes the mechanism of CNTF receptor signal transduction, and explores the similarities of CNTF and hematopoietic growth factor in signal transduction. To clarify the possible role of CNTF on the hematopoietic system.