近日,来自加拿大和中国科学家的一项最近研究成果表示,研究人员通过体内和体外实验证明激活toll-like receptor 3(TLR3)能够促进乳腺癌细胞向肿瘤干细胞(CSC)转化,产生干细胞特征,而TLR3的这种促CSC转化效应需要同时激活βcatenin和NF-κB信号通路才能发生。(源自:药品资讯网) Recently, a recent study by Canadian and Chinese scientists said the researchers demonstrated that activation of toll-like receptor 3 (TLR3) can promote the transformation of breast cancer cells into tumor stem cells (CSCs) and generate stem cell features through in vivo and in vitro experiments This pro-CSC transformation effect of TLR3 requires the simultaneous activation of the beta-catenin and NF-κB signaling pathways. (From: Drug Information Network)