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近年来,随着中西医结合工作的深入开展,中成药与西药并用防治疾病的情况,日益普遍。合理并用,可以减低毒性或增强疗效;并用不当,则会增加毒性或降低疗效,甚至产生危害。因此,研究中(成)药与西药之间的相互作用,在临床药学理论上和实践上都有重大意义。一、含金属离子的中成药与西药的相互作用1.凡由含有石膏、龙骨、龙齿、珍珠、牡蛎、蛤壳及瓦楞子等含钙较多的中药组成的中成药(见附表):(1)与四环素、土霉素、强力霉素、二甲胺四环素、
In recent years, with the in-depth development of the integration of Chinese and Western medicine, it has become increasingly common for both traditional Chinese and Western medicines to prevent and treat diseases. Rational use can reduce toxicity or enhance efficacy; if used improperly, it can increase toxicity or reduce efficacy, or even produce harm. Therefore, the study of the interaction between Chinese medicine and Western medicine has great significance both in theory and practice of clinical pharmacy. I. Interaction between proprietary Chinese medicines containing metal ions and Western medicine 1. All proprietary Chinese medicines containing gypsum, keel, dragon’s teeth, pearls, oysters, oyster hulls, and coriander seeds, etc. containing more calcium (see attached table) : (1) with tetracycline, oxytetracycline, doxycycline, dimethylamine tetracycline,