阵发性睡眠性血红蛋白尿(简称PNH)为一种慢性、持续性血管内溶血性疾病。阵发性发作,常在熟睡时发生血红蛋白尿。其发生溶血的机理一般认为红细胞存在着内在缺陷,由于睡眠时呼吸变浅,血中二氧化碳浓度增加,血PH 值降低,在补体的作用下促使有缺陷的红细胞溶血。诊断:1.血红蛋白尿(酱油色尿)的发作常与熟睡有关,白天睡眠亦可发作。多发生在青壮年,男 Paroxysmal nocturnal hemoglobinuria (PNH) is a chronic, persistent intravascular hemolytic disease. Paroxysmal seizures, often occur when sleeping hemoglobinuria. The mechanism of hemolysis is generally believed that there are inherent defects of red blood cells, due to shallow breathing during sleep, increased blood levels of carbon dioxide, blood PH value decreased in the role of complement to promote defective hemolysis of red blood cells. Diagnosis: 1. Hemoglobinuria (soy sauce color) episodes often associated with sleeping, sleep during the day can also attack. Occurred in young adults, men