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目的探讨妊娠期高血压疾病(HDCP)孕妇晚期子宫动脉多普勒血流监测变化及临床意义。方法选取2014年1-12月该院收治的妊娠晚期HDCP孕妇100例作为HDCP组,另选取同期正常健康孕妇98例作为对照组。于分娩前1周内行彩色多普勒超声检测孕妇子宫动脉的阻力指数(RI)及收缩期峰值血流速度与舒张末期血流速度的比值(S/D)。比较两组孕妇子宫动脉血流阻力指标变化,新生儿1min和5min的Apgar评分及出生体重。结果 HDCP组孕妇子宫动脉阻力指标明显高于对照组孕妇;HDCP胎儿生长发育受限,普遍存在缺氧现象,与对照组比较,差异均有统计学意义(P<0.05)。结论彩色多普勒超声检测能观察HDCP孕妇子宫动脉血流变化,对预测孕妇HDCP的发生及评估胎儿宫内状态具有一定的临床应用价值。
Objective To investigate the changes and clinical significance of late uterine artery Doppler blood flow in pregnant women with hypertensive disorder of pregnancy (HDCP). Methods From January to December 2014, 100 HDCP pregnant women in the third trimester of pregnancy were enrolled as the HDCP group. Another 98 healthy pregnant women of the same period were selected as the control group. The resistance index (RI) and the ratio of peak systolic to diastolic blood flow velocity (S / D) were measured by color Doppler ultrasonography within 1 week before delivery. The changes of blood flow resistance index of uterine arteries in two groups were compared. The Apgar score and birth weight of neonates at 1 minute and 5 minutes were compared. Results The resistance index of uterine artery in pregnant women with HDCP was significantly higher than that of pregnant women in HDCP group. HDCP fetal growth was restricted and hypoxia was common. Compared with the control group, the difference was statistically significant (P <0.05). Conclusions Color Doppler ultrasonography can observe the changes of uterine artery blood flow in HDCP pregnant women and has some clinical value in predicting the occurrence of HDCP in pregnant women and evaluating the intrauterine status.