雷公藤是一种主要以抑制方式起作用的中草药,近年已广泛用于治疗诸如系统性红斑狼疮、类风湿关节炎等免疫性疾病,取得了较好的疗效。对其作用机理的实验研究亦有一些报导,说明它对体液免疫和细胞免疫都有一定的抑制作用。但从细胞水平阐明其作用的确切环节尚乏资料,而且有的实验结果看来似乎互相矛盾。例如曾有报告指出,雷公 Tripterygium wilfordii is a kind of Chinese herbal medicine that mainly acts in an inhibitory manner. It has been widely used in recent years for the treatment of immune diseases such as systemic lupus erythematosus and rheumatoid arthritis, and has achieved good results. The experimental study of its mechanism of action has also been reported, indicating that it has a certain inhibitory effect on humoral and cellular immunity. However, there is still no information on the exact link to elucidate its role at the cellular level, and some experimental results seem to contradict each other. For example, there have been reports that