本文以 SD 大鼠为实验对象,测定在结扎其胆总管后的胃粘膜血流量、胃酸浓度、可滴定酸浓度、胃酸生成量、胃蛋白酶活性以及观察胃粘膜的结构变化。结果表明,上述各项指标均明显低于正常对照组,胃粘膜出现不同程度的病理学改变。证明,在阻塞性黄疸时,大鼠的胃粘膜已出现发生 AGML 的潜在因素。 In this paper, SD rats were used as experimental subjects to measure gastric mucosal blood flow, gastric acid concentration, titratable acid concentration, gastric acid production, pepsin activity and gastric mucosal structure changes after ligation of the common bile duct. The results showed that the above indicators were significantly lower than the normal control group, the gastric mucosa showed varying degrees of pathological changes. Proved that in obstructive jaundice, gastric mucosa in rats has emerged a potential factor for the occurrence of AGML.