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近年来许多长链非编码RNA（lncRNA）被发现，lncRNA表达量的异常与肿瘤的发生、发展密切相关，根据其作用可分为促进肿瘤作用 lncRNA 和抑制肿瘤作用 lncRNA，使 lncRNA 有望成为新型肿瘤诊断标志物和治疗靶点，用于肿瘤诊断、治疗和复发的监测。相关研究发现，lncRNA与膀胱肿瘤细胞的增殖、浸润、转移和复发密切相关。目前关于 lncRNA 在膀胱肿瘤中的作用大多来自其表达水平的差异，提示调控 lncRNA 表达量可能为膀胱肿瘤的诊断和治疗提供新依据。“,”Many long non-coding RNAs ( lncRNA) were found in recent years, and the abnormal lncRNA expression is closely related to the occurrence and development of tumor.lncRNA is expected to become a new cancer diagnosis marker and therapeutic target.lncRNA can be divided into the tumor-pro-moting and tumor-inhibiting according to the function,and it can be used for the carcinoma diagnosis, treatment and relapse monitoring.Some studies suggested that lncRNA was closely related to bladder tumor cell proliferation,invasion,metastasis and recurrence.Most of the reports on lncRNA role in bladder tumor are about the different expression level,indicating that regulating the expression level of lncRNA may pro-vide a new basis for the diagnosis and treatment of bladder tumor.