论文部分内容阅读
目的探讨孕妇桡动脉血流图的监测在预测子痫前期中的应用价值,以准确识别有高危风险的孕妇,早期预测子痫前期的发生,减少母婴伤害。方法对产前检查无高血压、糖尿病、心、肝、肾等并发症,孕周为16～36周的10 433例孕妇分为预测组(5 223例)和对照组(5 210例)。预测组应用桡动脉血流图进行监测,每4周重复1次,对预测阳性者每2周重复测定并给予干预措施;对照组直到发现子痫前期症状时才给予干预。随访两组患者至分娩结束,对两组患者子痫前期的发生率、发病程度及新生儿体质量进行比较。结果预测组中子痫前期及子痫的发病率分别为11.2%和0.11%,对照组中子痫前期及子痫的发病率分别为13.5%和0.29%(P<0.05);新生儿生长受限率在预测组和对照组中分别为5.11%和7.06%(χ2=15.38,P<0.01);对照组中子痫前期的病情程度明显较预测组重(P<0.05);妊娠期高血压疾病监测系统在不同孕周预测子痫前期的敏感度不同,预测子痫前期的阳性符合率随孕周增加而增加。结论应用妊娠期高血压疾病监测系统及动态桡动脉血流动力学指标的改变早期预测子痫前期,对预测阳性者给予临床指导,可降低其发病率并防止病情发展,改善孕产妇和围产儿的结局。
Objective To investigate the value of monitoring radial artery blood flow in pregnant women in the prediction of preeclampsia in order to accurately identify pregnant women at high risk and to predict the occurrence of preeclampsia and reduce the harm of maternal and infant. Methods A total of 10 433 pregnant women with gestational age from 16 to 36 weeks were divided into the prediction group (5 223 cases) and the control group (5 210 cases) for prenatal examination without complications of hypertension, diabetes, heart, liver and kidney. The prediction group was monitored by radial artery blood flow graph, repeated once every 4 weeks, repeated every 2 weeks for the predicted positives and given interventions; the control group was not given intervention until the symptoms of preeclampsia were found. Two groups of patients were followed up until the end of delivery, the incidence of preeclampsia in both groups, the incidence and neonatal body weight were compared. Results The incidences of preeclampsia and eclampsia in the predicted group were 11.2% and 0.11%, respectively. The incidences of preeclampsia and eclampsia in the control group were 13.5% and 0.29%, respectively (P <0.05). The neonatal growth In the control group, the prevalence of preeclampsia was significantly higher than that in the predictive group (P <0.05); the rate of pregnancy in preeclampsia was 5.11% and 7.06% respectively (χ2 = 15.38, P <0.01) The disease surveillance system has different sensitivities in predicting preeclampsia at different gestational weeks, and the positive coincidence rate in predicting preeclampsia increases with gestational age. Conclusion The application of monitoring system of hypertensive disorder complicating pregnancy and dynamic hemodynamic changes of radial artery in early prediction of preeclampsia, to predict the positive clinical counseling can reduce the incidence and prevent the progression of the disease, improve the maternal and perinatal The outcome.