一、概念:按照临床病程的不同,组织细胞增生症起初被分为三种独立的疾病,即①Letterer-Siwe病(下称L-S病),见于婴幼儿,常迅速死亡;②Hand-Schller-Christain病(下称H-S-C病),发生于较大的儿童,病程为慢性;③骨嗜酸性细胞肉芽种,在年长的儿童和成人发病,为局限于骨内的肉芽肿性病变.但是,随着临床资料的积累,人们发现上 First, the concept: According to the different clinical course, histiocytosis initially divided into three independent diseases, namely ① Letterer-Siwe disease (hereinafter referred to LS disease), seen in infants and young children, often died quickly; ②Hand-Schller- Christain disease (hereinafter referred to as HSC disease), occurs in larger children, the course of chronic disease; ③ bone eosinophilic granuloma, in older children and adults, is limited to intraosseous granulomatous lesions.However, As clinical data accumulates, people find it