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目的 探讨甲亢患者血脂和总蛋白的变化与甲状腺激素的关系及临床意义。方法 用免疫化学发光技术检测 71例患者和 32例健康对照组血清游离T3(FT3)、游离T4(FT4) ,以生化仪检测甘油三酯 (TG)、胆固醇(TCH)、高密度脂蛋白胆固醇 (HDL C)和总蛋白的含量。结果 甲亢患者血脂含量明显低于对照组 (P <0 0 5 ) ,与FT3、FT4呈反比关系。总蛋白含量也明显低于对照组 (P <0 0 5 ) ,其变化与FT3、FT4浓度有关。结论 甲亢患者血脂和总蛋白明显降低 ,且可作为判断甲亢病情和疗效的指标之一。
Objective To investigate the relationship between serum lipid and total protein and thyroid hormone in patients with hyperthyroidism and its clinical significance. Methods The levels of serum free T3 (FT3) and free T4 (FT4) in 71 patients and 32 healthy controls were detected by immunochemiluminescence. The level of triglyceride (TG), cholesterol (TCH), high density lipoprotein cholesterol (HDL C) and total protein content. Results The serum lipid level of patients with hyperthyroidism was significantly lower than that of the control group (P <0.05), and inversely proportional to FT3 and FT4. The total protein content was also significantly lower than that of the control group (P <0 05). The changes were related to the concentrations of FT3 and FT4. Conclusion Serum lipids and total protein in patients with hyperthyroidism were significantly lower, and may be used as one of the indicators to judge the condition and efficacy of hyperthyroidism.