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目的探讨术后不同治疗方法对子宫内膜异位症伴不孕患者妊娠率的影响。方法收集该院2012年1月-2014年1月子宫内膜异位症患者150例,所有患者行腹腔镜确诊、分期并手术治疗,术后根据患者意愿分为孕三烯酮组、亮丙瑞林组、对照组,观察3组妊娠情况。结果比较3组患者术后1年和2年妊娠率,差异均无统计学意义(P>0.05);比较不同rAFS分期患者术后1年和2年妊娠率,差异均具有统计学意义(P<0.01);比较不同r-AFS分期的3组患者术后妊娠情况,Ⅰ~Ⅱ期的3组患者术后1年和2年妊娠率比较,差异均无统计学意义(P>0.05);Ⅲ~Ⅳ期的3组患者术后1年和2年妊娠率比较,差异均具有统计学意义(P<0.05)。结论 r-AFS分期是影响患者术后妊娠率的直接因素。在促进r-AFS分期的Ⅲ-Ⅳ期患者生育能力恢复方面,腹腔镜联合药物治疗优于单纯腹腔镜手术。
Objective To investigate the effect of different postoperative treatment methods on pregnancy rate in patients with endometriosis and infertility. Methods 150 patients with endometriosis in our hospital from January 2012 to January 2014 were collected. All patients were diagnosed by laparoscopy, staged and operatively treated. According to the patients’ wishes, all patients were divided into gestrinone group, Ruilin group, control group, observe the pregnancy status of the three groups. Results There was no significant difference in the 1-year and 2-year pregnancy rates between the three groups (P> 0.05). The difference of 1-year and 2-year pregnancy rates between different rAFS patients was statistically significant (P <0.01). There was no significant difference in the pregnancy rates among the three groups of patients with different stages of r-AFS after 1-year and 2-year follow-up (P> 0.05). The difference of 1-year and 2-year pregnancy rates between the three groups of patients in stage Ⅲ ~ Ⅳ was statistically significant (P <0.05). Conclusion r-AFS staging is a direct factor affecting the rate of postoperative pregnancy. Laparoscopy combined with drug treatment was superior to simple laparoscopic surgery in the recovery of fertility in stage III-IV patients with r-AFS staging.