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目的:观察黄芪三仙汤对绝经后骨质疏松症骨密度及骨矿含量指标的的影响。方法:将83例患者随机分为2组,治疗组42例,予口服黄芪三仙汤(由仙茅、淫羊藿、黄芪、三七等组成)治疗;对照组41例,予骨疏康(1包,3次/日)治疗,2组疗程均为3个月。再以同样方法测定腰椎骨密度及骨矿含量的变化情况。结果:治疗后患者腰椎的骨密度及骨矿含量变化,总有效率治疗组为78.6%,对照组为73.2%。2组比较,差异无显著性意义(P>0.05)。治疗后2组骨密度及骨矿含量均有提高,与治疗前比较,差异有显著性意义(P<0.05),两种药物均有治疗骨质疏松症作用,但黄芪三仙汤的效果更好。结论:黄芪三仙汤通过补肾益气、活血通络,可明显提高腰椎骨密度及骨矿含量,治疗绝经后骨质疏松症有较好的临床疗效。
Objective: To observe the effect of Huangqi Sanxian decoction on bone mineral density and bone mineral content in postmenopausal osteoporosis. METHODS: Eighty-three patients were randomly divided into two groups. The treatment group was treated with oral administration of Huangqi Sanxian Decoction (composed of Curculigo japonica, Epimedium, Astragalus membranaceus, Panax notoginseng, etc.) in 42 patients; 41 patients in the control group were treated by Gu Shukang (1 pack, 3 times/day) treatment, 2 groups of treatment are all 3 months. The same method was used to determine changes in bone mineral density and bone mineral content in the lumbar spine. Results: After treatment, the bone mineral density and bone mineral content of the lumbar spine were changed. The total effective rate was 78.6% in the treatment group and 73.2% in the control group. There was no significant difference between the two groups (P>0.05). After treatment, bone mineral density and bone mineral content increased in both groups. Compared with before treatment, the difference was significant (P<0.05). Both drugs had the effect of treating osteoporosis, but the effect of Huangqi Sanxian Decoction was more effective. it is good. Conclusion: Huangqi Sanxian Decoction can significantly increase the bone mineral density and bone mineral content in lumbar vertebrae by tonifying kidney and replenishing Qi and activating blood circulation. It has a good clinical effect in the treatment of postmenopausal osteoporosis.