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糖尿病患者常有脂质代谢障碍。红细胞膜的脂质主要是胆固醇和磷脂,经过治疗,胆固醇代谢障碍容易矫正,而磷脂的改变比较顽固,且与病史及并发症有关。作者研究糖尿病患者红细胞膜脂质成分的变化以及用不同降糖疗法的矫正作用。 初次查出的非胰岛素依赖型糖尿病(NIDDM),46例,女35例,男11例,年龄46～60岁。按治疗方法分3组,第1组12例,只用饮食疗法。第2组20例,用甲磺吡脲(氨磺丁脲)治疗。第3组14例,用缩二胍治疗。观察6～8月,糖代谢的代偿作用
Diabetic patients often have dyslipidemia. Erythrocyte membrane lipid is mainly cholesterol and phospholipids, after treatment, cholesterol metabolism disorders easy to correct, and phospholipid changes more stubborn, and with the history and complications related. The authors studied the changes in the lipid composition of the erythrocyte membrane in patients with diabetes and the corrective action with different glucose-lowering therapies. The first non-insulin dependent diabetes mellitus (NIDDM), 46 cases, 35 females, 11 males, aged 46 to 60 years. Divided by treatment 3 groups, the first group of 12 patients, only diet therapy. The second group of 20 cases, with metsulfuron-methyl (sulfapyridine) treatment. Group 3, 14 cases treated with biguanide. Observed from June to August, the compensatory role of glucose metabolism