在过去30年中,急性心肌梗塞(AMI)的治疗有了巨大进展。60年代直流电转复的应用导致冠心病监护概念的形成,其焦点是控制心律失常。在动物实验与人冠脉急性闭塞常发生复杂的室性早搏,并以室速和室颤而告终。冠状监护室抗心律失常治疗目的是预防性抑制复杂心律失常导致的室速与室颤,从而减少早期死亡率。选用利多卡因是因它有效、半衰期短,易于静脉给药而很少心血管毒性。它可清除短暂的电不稳定性,从而防止室颤,但它对急性死亡的效益常不肯定,且除颤对远期预后并无影响。在20年中,利多卡 In the past 30 years, tremendous progress has been made in the treatment of acute myocardial infarction (AMI). The application of DC in 60s led to the formation of the concept of coronary heart disease monitoring, the focus of which is to control arrhythmias. In animal experiments and acute coronary occlusion often occurs in complex premature ventricular contractions, and VT and terminal ventricular fibrillation. Coronary Care Anti-arrhythmic Therapies The goal of prophylaxis is to prevent ventricular tachycardia and ventricular fibrillation resulting from complex arrhythmias, thereby reducing early mortality. Use of lidocaine because it is effective, short half-life, easy intravenous administration and little cardiovascular toxicity. It clears transient electrical instability and thus prevents ventricular fibrillation, but its efficacy in acute death is often undetermined, and defibrillation has no effect on long-term prognosis. In 20 years, Lidoca