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目的:评价中文版简明健康状况调查表（SF-36量表）在慢型克山病患者生存质量调查中应用的信度与效度，为该人群生活质量研究及治疗康复评价提供科学依据。方法:2017年8月，采用整群随机抽样方法，抽取甘肃省平凉市2017年家庭病床自我管理治疗的175例慢型克山病患者为调查对象，收集人口学资料和病情资料；并采用中文版SF-36量表进行生存质量调查。应用分半信度和克朗巴赫α系数（Cronbach′s α系数）评价SF-36量表的信度，因子分析法、相关性及组间差异分析评价SF-36量表的效度。结果:SF-36量表的分半信度值为0.916，Cronbach′s α系数为0.869。因子分析从SF-36量表的8个维度中提取出3个公共因子，3个公共因子对总方差的累计贡献率为72.08%；除情感职能与躯体疼痛维度的相关系数（n r）外，SF-36量表总得分与各维度得分及各维度得分之间的n r值在0.140 ~ 0.769；除躯体疼痛维度外，不同心功能分级患者的生存质量生理机能、生理职能、一般健康状况、精力、社会功能、情感职能、精神健康维度得分比较差异均有统计学意义（n F = 4.66、10.73、6.77、14.61、5.58、9.57、7.10，n P均< 0.05）。n 结论:中文版SF-36量表在评价慢型克山病患者的生存质量中具有较好的信度和效度，可用于慢型克山病患者的生存质量评价。“,”Objective:To evaluate the reliability and validity of the Chinese version of concise health status questionnaire (SF-36 scale) in evaluating the quality of life of patients with chronic Keshan disease, and to provide a scientific basis for studying the quality of life and the evaluation of treatment and rehabilitation of this population.Methods:In the August 2017, using cluster random sampling method, 175 patients with chronic Keshan disease treated by self-management of family beds in Pingliang City, Gansu Province in 2017 were selected as survey subjects, and demographic and disease data were collected. The Chinese version of SF-36 scale was used to investigate the quality of life. Split-half reliability and Cronbach\'s α coefficient were used to evaluate the reliability of the SF-36 scale; the factor analysis, correlation and differences between groups were used to evaluate the validity of the SF-36 scale.Results:The split-half reliability value of SF-36 scale was 0.916, and the Cronbach\'s α coefficient was 0.869. Factor analysis extracted 3 common factors from 8 dimensions of SF-36 scale, and the cumulative contribution rate of the 3 common factors to the total variance was 72.08%. In addition to the correlation coefficient (n r) between Role-Emotional and Bodily Pain dimension, the n r value between total score and the scores of each dimension, and the scores of each dimension of SF-36 scale were 0.140 - 0.769. Except for the Bodily Pain dimension, there were statistically significant differences in the scores of Physiological Functioning, Role-Physical, General Health, Vitality, Social Functioning, Role-Emotional, and Mental Health dimension of the quality of life of patients with different grades of cardiac function (n F = 4.66, 10.73, 6.77, 14.61, 5.58, 9.57, 7.10, n P < 0.05).n Conclusion:The Chinese version of SF-36 scale has good reliability and validity in evaluating the quality of life of patients with chronic Keshan disease, and can be used to evaluate the quality of life of the patients.