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目的探讨大颗粒酸蚀喷砂(Sandblasted/Large-grit/Acide-tched,SLA)表面处理的种植体与SLA表面喷涂钽(Ta)形成纳米复合表面的种植体对种植体周围炎发生发展的影响。方法 6只Beagle犬双侧前磨牙延期植入2种不同表面种植体。从左侧远中到右侧远中依次将植体记为1~6号,3、4号种植体设置非绑线的基线组,其余于基台颈部丝线结扎的方法建立犬种植体周围炎模型。分别在建模后四次对植体进行菌斑指数(plaque index,PI)、改良出血指数(modified Sulcus Bleeding Index,m SBI)、种植体周探诊深度(probing depth,PD)等临床指标测量,通过手术直观评价、显微CT扫描、组织学评价相结合观察种植体周骨缺损程度,对实验结果采用重复测量方差分析。结果绑线的SLA组PI、m SBI、PD、垂直缺损与水平缺损深度等指标均显著高于绑线的SLA+Ta组(P<0.05);显微CT扫描和组织学评价相结合观察可见绑线的SLA组较绑线的SLA+Ta组种植体周骨缺损明显。结论 SLA表面喷涂钽形成纳米复合表面的种植体较SLA表面处理的种植体延缓种植体周围炎的发生发展并减轻其症状。
OBJECTIVE: To investigate the effect of implanting sandblasted / large-grit / Acide-tched (SLA) surface treatment and implanting tantalum (Ta) on the surface of SLA nanocomposite to influence the development of peri-implantitis . Methods Six Beagle dogs bilateral premolar teeth were implanted with two different surface implants. From left to right to the far side of the implant in turn as No. 1 to 6, No. 3,4 implants set non-tied baseline group, the rest in the abutment neck ligation method to establish a dog implant around Yan model. The plaque index (PI), modified Sulcus Bleeding Index (m SBI) and probing depth (PD) were measured four times after modeling respectively. The degree of peri-implant defect was observed by visual evaluation of operation, micro-CT scan and histological evaluation. Repeated measures of variance (ANOVA) were used to analyze the experimental results. Results The index of PI, m SBI, PD, vertical defect and horizontal defect depth of SLA group were significantly higher than that of SLA + Ta group (P <0.05). The combination of microscopic CT scan and histological evaluation showed that Compared with the SLA + Ta group, the bone defect in the SLA group was more obvious. CONCLUSIONS: The SLA surface-coated tantalum nanocomposite implants delayed the onset and reduction of peri-implantitis compared with SLA-treated implants.