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五峰县宫颈癌高发区流行因素病例对照配对(172对)的研究结果:从55个因素中筛选出有显著意义的相对危险因素有宫颈糜烂、丈夫包皮过长、家族肿瘤史、性格因素(闷气、急燥)、以往有重大伤心事、产褥期不洁、经济收入较差、阴道白带多、同房年龄过早,阴道细胞巴氏分级Ⅱ级以上、HSV-2抗原阳性、HSV-2抗体阳性、子宫颈白斑、夫妻感情不好等14个因素。同时对性因素、精神因素、经济因素、家族肿瘤史因素及子宫颈糜烂等五大因素作了综合研究,揭示组合2、3、4、5个因素分别得到病例组的相对危险性(RR)高于对照组的2.65～1600倍,提出致子宫颈癌是多因素综合作用的观点。并相应提出了在高发区应采取综合防治措施的具体建议和进一步开展病因、诊断及治疗综合研究的意见。
Wufeng County, the prevalence of cervical cancer in high incidence of case-control paired (172 pairs) of the results of the study: Out of 55 factors in the screening of significant risk factors are cervical erosion, her husband’s prepuce, family history of cancer, personality factors , Rapid dry), in the past there are major sad things, unclean puerperal, poor income, vaginal vaginal discharge, premature intercourse room, vaginal cell pasteurization grade Ⅱ or more, HSV-2 antigen positive, HSV-2 antibody positive, Cervical leukoplakia, marital relationship is not good, 14 factors. At the same time, a comprehensive study was made on five factors including sexual factors, mental factors, economic factors, family history of cancer and cervical erosion. The results showed that the relative risk (RR) 2.65 ~ 1600 times in the control group, put forward the view that cervical cancer is a multi-factor comprehensive effect. And accordingly put forward specific recommendations for comprehensive prevention and control measures to be taken in high incidence areas and suggestions for further carrying out a comprehensive study on etiology, diagnosis and treatment.