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目的观察四联药物治疗幽门螺旋杆菌(Hp)相关性胃溃疡患者的临床效果。方法选择医院2013年9月-2015年10月收治的Hp相关性胃溃疡患者80例,按随机数字法分为试验组和对照组各40例,试验组采用四联药物治疗,对照组采用三联药物治疗,比较2组的治疗总有效率、Hp根除率及复发率。结果试验组总有效率为95.0%高于对照组的72.5%,Hp根除率为95.0%(38/40)高于对照组的70.0%(28/40),复发率为5.0%(2/40)低于对照组的15.0%(6/40),差异均有统计学意义(P<0.05)。结论四联药物治疗Hp相关性胃溃疡患者疗效显著,Hp根除率高,复发率低,临床推广价值高。
Objective To observe the clinical effect of quadruple drug therapy in patients with gastric ulcer associated with Helicobacter pylori (Hp). Methods Eighty patients with Hp-associated gastric ulcer admitted from September 2013 to October 2015 in our hospital were divided into experimental group (40 cases) and control group (40 cases) by random number method respectively. The control group was treated with triple therapy Drug treatment, the two groups compared the total effective rate, Hp eradication rate and recurrence rate. Results The total effective rate was 95.0% in the trial group, 72.5% in the control group, 95.0% (38/40) in the Hp group and 70.0% (28/40) in the control group. The recurrence rate was 5.0% (2/40) ) Was lower than 15.0% (6/40) in the control group, the difference was statistically significant (P <0.05). Conclusions Quadruple drug treatment of Hp-related gastric ulcer patients with significant effect, Hp eradication rate, recurrence rate is low, clinical promotion of high value.