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20世纪40年代以来,连续的肝活检组织学研究已证实,急性病毒性肝炎可转变成慢性肝炎和肝硬化。乙型肝炎抗原(HBAg)的发现为确立肝硬化与乙型肝炎的关系奠定了基础。甲型肝炎与肝硬化的关系不太明确。一般认为,甲型肝炎的慢性后遗症比乙型少见。
Since the 1940s, successive studies of liver biopsy histology have demonstrated that acute viral hepatitis can be converted to chronic hepatitis and cirrhosis. The discovery of hepatitis B antigen (HBAg) laid the foundation for the establishment of the relationship between cirrhosis and hepatitis B. The relationship between hepatitis A and cirrhosis is not clear. Generally believed that chronic hepatitis A sequelae less than B type.