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国外利用蛇毒进行免疫研究早在1887年就已开始。于1894年 Galmette 用眼镜蛇毒对家兔和豚鼠进行免疫,制备了抗眼镜蛇毒血清。此后就有较多的科学工作者从事于抗蛇毒血清的研究工作。在这八十多年中,世界上已有20多个国家利用50多种蛇毒研制成70余种单价和多价抗蛇毒血清。长期临床实践证明:抗蛇毒血清系治疗毒蛇咬伤特异性强疗效显著的制品,应用愈早,效果越好。近十年来,上海生物制品研究所、浙江省中医研究所和浙江医科大学共同协作研制精制抗蝮蛇毒血清和精制抗五步蛇毒血清。继之,1976年广州医学院与上海生物制品研究所协
Foreign use of snake venom for immunization as early as 1887 has already begun. Galmette in 1894 with cobra venom on rabbits and guinea pigs immunized against cobra venom serum. Since then there are more scientific workers engaged in anti-snake venom serum research. In these 80 years, more than 20 countries in the world have developed more than 70 kinds of monovalent and multivalent anti-snake venom serums with over 50 kinds of snake venoms. Long-term clinical practice has proved that anti-snake venom serum treatment of snake bites specific efficacy of significant products, the application of the earlier, the better. Over the past decade, the Shanghai Institute of Biological Products, Zhejiang Institute of Traditional Chinese Medicine and Zhejiang Medical University collaborative research and development of refined anti-viper venom serum and refined anti-five-step snake venom serum. Then, in 1976, Guangzhou Medical College and Shanghai Institute of Biological Products Association