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目的:探讨检测人血清β-人绒毛膜促性腺激素(β-hCG)及子宫内膜厚度与不明位置妊娠(PUL)妇女妊娠结局的关系。方法:回顾性分析该院妇科门诊及住院部2013年7月~2014年8月就诊及收治的具有“停经、尿妊娠试验阳性”的98例PUL患者的就诊资料,根据妊娠结局分为宫内孕组(37例)、宫外孕组(26例)、自然流产组(35例),对3组患者的β- CG、子宫内膜厚度值及相关激素水平进行比较分析。结果:早期检测PUL患者的β-hCG、子宫内膜厚度、β-hCG比值、P值、E2值在3组间差异均有统计学意义(P<0.05);宫外孕组的β-hCG、子宫内膜厚度、β-hCG比值、P值、E2值均显著低于宫内孕组、自然流产组(P<0.05);自然流产组的β-hCG、子宫内膜厚度、β-hCG比值、P值、E2值均显著低于宫内孕组(P<0.05)。结论:对于PUL妇女早期检查β-hCG、子宫内膜厚度对判定宫外孕及流产有一定的临床价值。
Objective: To investigate the relationship between β-human chorionic gonadotropin (β-hCG), endometrial thickness and pregnancy outcome in unknown pregnant women (PUL). Methods: A retrospective analysis of the hospital gynecological outpatient and inpatient department from July 2013 to August 2014 treatment and admitted with “menopause, urine pregnancy test positive” in 98 cases of PUL patient treatment information, according to the pregnancy outcome is divided into Intrauterine pregnancy group (37 cases), ectopic pregnancy group (26 cases) and spontaneous abortion group (35 cases). The β-CG, endometrial thickness and related hormone levels in three groups were compared. Results: There were significant differences in β-hCG, endometrial thickness, β-hCG ratio, P value and E2 between the three groups in the early detection of PUL (P <0.05) Intimal thickness, β-hCG ratio, P value and E2 value were significantly lower than those in intrauterine pregnancy group and spontaneous abortion group (P <0.05). Β-hCG, endometrial thickness, β-hCG ratio in spontaneous abortion group, P value and E2 value were significantly lower than those in intrauterine pregnancy group (P <0.05). Conclusion: For early detection of β-hCG in women with PUL, the thickness of endometrium has some clinical value in judging ectopic pregnancy and abortion.