右美托咪啶(DEX)是α2肾上腺素受体激动剂美托咪啶的右旋异构体,高选择性激动α2肾上腺素受体,抑制交感神经兴奋,产生镇静、镇痛和抗焦虑作用,无呼吸抑制和不干扰脑电生理活动,不良反应少。因此,DEX被广泛应用于临床。研究发现,DEX对心脏、大脑、肝脏、肾脏、肺等器官具有一定的保护作用。 Dexmedetomidine (DEX), the dextrorotatory isoform of the [alpha] 2 adrenoceptor agonist medetomidine, agonizes the [alpha] 2 adrenoceptor with high selectivity and suppresses sympathetic activity, producing sedation, analgesia and anxiety Role, no respiratory depression and does not interfere with brain electrophysiology, adverse reactions. Therefore, DEX is widely used in clinical practice. The study found that DEX on the heart, brain, liver, kidney, lung and other organs have a protective effect.