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目的探讨研究异甘草酸镁联合门冬氨酸鸟氨酸治疗乙肝肝硬化肝性脑病的临床疗效。方法选取我院收治的乙肝肝硬化肝性脑病患者36例,随机分为两组,A组(18例)应用异甘草酸镁联合门冬氨酸鸟氨酸治疗,B组(18例)应用门冬氨酸鸟氨酸治疗,观察比较两组的临床疗效。结果 A组(94.44%)疗效优于B组(83.33%),且A组治疗方法较B组起效快;两组治疗后血氨、血胆红素、ALT水平均显著下降(P<0.01),且A组较B组下降更显著(P<0.05)。结论门冬氨酸鸟氨酸治疗乙肝肝硬化肝性脑病的临床疗效好,在此基础上联合应用异甘草酸镁,疗效更佳,作用更迅速,该联合治疗方法值得临床推广应用。
Objective To investigate the clinical efficacy of magnesium isoglycyrrhizinate combined with aspartate ornithine in the treatment of hepatic cirrhosis with hepatitis B cirrhosis. Methods Thirty-six patients with hepatitis B cirrhosis and hepatic encephalopathy admitted to our hospital were randomly divided into two groups. Group A (18 cases) was treated with magnesium isoglycyrrhizinate combined with aspartate ornithine, while group B (18 cases) Acid ornithine treatment, observed and compared the clinical efficacy of the two groups. Results The efficacy of group A (94.44%) was better than that of group B (83.33%), and the treatment of group A was faster than that of group B. The levels of serum ammonia, bilirubin and ALT decreased significantly in both groups after treatment (P <0.01 ), And group A was more significant than group B (P <0.05). Conclusion Aspartate ornithine has a good curative effect on hepatitis B cirrhosis and hepatic encephalopathy. On the basis of this, the combination of magnesium isoglycyrrhizinate has better curative effect and more rapid effect. The combination therapy is worthy of clinical application.