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1963年以来,脂肪肝脑病综合征报导已有500例以上,但其病因尚不清楚。大多数病人在脑病前有病毒样疾病。本文报导1973年起的全国脂肪肝脑病综合征监督系统所收集的资料及1974年2月和3月间发生的一次全国性脂肪肝脑病综合征暴发及其与乙型流感的流行病学关系。于1973年12月15日至1974年6月30日发生脂肪肝脑病综合征379例,其中316例发生在1974年2月和3月。379例中男179例,女200例。平均年龄11岁,11～14岁者占总数37％,16岁以上仅占4％。超过18岁者仅1例为28岁女性,经尸检证实。88％的患者在
Since 1963, more than 500 cases of fatty liver encephalopathy syndrome have been reported, but its etiology is not yet clear. Most patients have a virus-like illness before their encephalopathy. This article reports data collected from the national surveillance system for fatty liver and encephalopathy since 1973 and a nationwide outbreak of fatty liver encephalopathy syndrome in February and March 1974 and its epidemiological relationship with influenza B virus. 379 cases of fatty liver disease syndrome occurred from December 15, 1973 to June 30, 1974, of which 316 cases occurred in February and March 1974. There were 179 males and 200 females in 379 cases. The average age of 11 years old, 11 to 14 years of age accounted for 37% of the total, over the age of 16 only 4%. Only one patient over the age of 18 was 28 years old and confirmed by autopsy. 88% of patients in the