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自身免疫性溶血性贫血(AIHA)是由于体内产生与自身红细胞抗原起反应的自身抗体,使红细胞破坏而引起的一种溶血性疾病。一、病因小儿AIHA以继发性为多见。本院与上海新华儿童医院及上海市儿童医院61例中,有原因可查或有相关因素者占77%,其中感染性疾病如呼吸道感染、婴儿肝炎综合征、乙型肝炎、肠道感染、传染性单核细胞增多症及水痘等33例,系统性红斑狼疮及幼年型类风湿共3例,发生在牛痘接种后1例,用药物后3例。
Autoimmune hemolytic anemia (AIHA) is a haemolytic disease caused by the destruction of erythrocytes due to autoantibodies that react with their own red cell antigens in the body. First, the etiology of children with AIHA secondary to more common. Our hospital and Shanghai Xinhua Children’s Hospital and Shanghai Children’s Hospital 61 cases, there are reasons for the investigation or related factors accounted for 77%, of which infectious diseases such as respiratory tract infection, infant hepatitis syndrome, hepatitis B, intestinal infections, Infectious mononucleosis and chickenpox in 33 cases, systemic lupus erythematosus and juvenile rheumatoid in 3 cases occurred in vaccinated vaccinia in 1 case, after medication in 3 cases.