前言 振动听觉病(VAD)存在于那些长期暴露在低频(<500Hz)、高强度(>90dB)的噪声中的航空工业职业人员。这种疾病伴有较高的呼吸系统感染的易感性。这里我们研究正常鼠长期暴露在这类环境应激下是否会导致免疫功能的变化,而这种变化是通过动物脾的不同淋巴细胞亚群的变化来体现的。方法用流动血细胞计数器分析BALB/c鼠的脾淋巴细胞,这些鼠在三个月内暴露在低频、高强度噪声中共计 Preface Vibration Auditory Diseases (VADs) exist in aviation industry professionals who have long been exposed to low frequency (<500Hz), high intensity (> 90dB) noise. This disease is associated with a high susceptibility to respiratory infections. Here we study whether long-term exposure of normal rats to such environmental stress will result in changes in immune function, which is manifested by changes in different lymphocyte subsets of the animal spleen. Methods The splenic lymphocytes of BALB / c mice were analyzed by flow cytometry and these mice were exposed to low frequency, high intensity noise for a total of three months