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目前血管紧张素Ⅱ(AⅡ)与痛和镇痛的关系尚不一致。有人用甩尾法证明AⅡ有镇痛作用,fi可被纳洛酮桔抗。但有行为学研究表明脑室注射AⅡ可对抗吗啡镇痛。近来认为AⅡ是内源性抗阿片物质之一。本文用电生理方法在脊髓和丘脑水平观察AⅡ对伤害性神经元放电及吗啡效应的影响。实
At present, the relationship between angiotensin Ⅱ (AⅡ) and pain and analgesia is still not consistent. Some people use the tail flick method to prove A Ⅱ analgesic effect, fi naloxone citrate can be anti. However, behavioral studies have shown that intracerebroventricular injection of A Ⅱ can antagonize morphine analgesia. Recently, AII is considered as one of the endogenous anti-opioids. In this paper, electrophysiological methods in the spinal cord and thalamic levels of A Ⅱ on the nociceptive discharge and morphine effects. real