腹泻是死亡和病废因素之一。急性腹泻绝大部分由细菌、病毒和原生物引起。大部分细菌性腹泻是非侵入性的而由肠毒索引起肠分泌的结果。慢性腹泻常难以治疗而成为临床上的困难问题。阿片及其衍生物通常是广泛使用的抗腹泻药 Diarrhea is one of the factors of death and illness. The vast majority of acute diarrhea caused by bacteria, viruses and protists. Most bacterial diarrhea is noninvasive and intestinal secretion results from enterotoxin. Chronic diarrhea is often difficult to treat and becomes a clinically difficult problem. Opiates and their derivatives are commonly used antidiarrheal drugs