香烟烟雾浓缩物和大量吸烟者的尿中提取物中,含有诱发细菌突然变异和使淋巴球去氧核糖核酸(DNA)生成障碍的物质,这种物质也容易引起吸烟者末稍淋巴球染色体的异位。精子形成包括细胞数的急剧增加和增殖细胞的分化成熟,前者需DNA的生成,后者则需蛋白的生成。当睾丸内分泌机能障碍、睾丸温度持续上升(高于37℃)或给予核酸代谢阻止剂、蛋白生成阻止剂时,精子形成很易受到阻碍。此时不仅精子数量减少,畸形精子的发现率也升高。同样现象可见于放射线照射治疗及慢性肾功能不全、糖尿病等伴有蛋白生成障碍 The urine extracts of cigarette smoke concentrates and smokers contain substances that induce sudden mutations in the bacteria and impair the production of lymphoblastoid DNA (DNA), which are also likely to cause the chromosomes of the distal lymphocytes of smokers Ectopic. Spermatogenesis involves a dramatic increase in cell numbers and differentiation and proliferation of proliferating cells, the former requiring the production of DNA and the latter requiring protein production. When testicular endocrine dysfunction, testicular temperature continues to rise (above 37 ℃) or given nucleic acid metabolism inhibitor, protein production inhibitor, sperm formation is easily hindered. At this point not only to reduce the number of sperm, abnormal sperm discovery rate also increased. The same phenomenon can be seen in the treatment of radiation and chronic renal insufficiency, diabetes and other accompanied by protein production disorders