阿斯匹林是一种常用的解热镇痛和消炎抗风湿的药物。长期服用或用较大剂量时易对胃肠道粘膜产生刺激作用,引起上腹部不适,恶心,有时引起不易察觉的胃出血。肠溶阿斯匹林片虽已在临床广泛使用,但受胃排空影响较大,生物利用度低。 Aspirin is a commonly used antipyretic and anti-inflammatory antirheumatic drug. Long-term use or use of larger doses of gastrointestinal mucosa is easy to stimulate, causing upper abdominal discomfort, nausea, and sometimes caused by imperceptible stomach bleeding. Enteric-coated aspirin tablets, although widely used in clinical practice, are greatly affected by gastric emptying and have low bioavailability.