论文部分内容阅读
42例经血或骨髓培养证实的耐药伤寒,随机分为5组。对照组静脉滴注氨苄青霉素,每日5～6g,并加用庆大霉素每日16～24万U,疗程14～21天。4组治疗组分别给予氟哌酸0.3～0.4g每日3次,甲氟哌酸0.4g每日2次,氟嗪酸0.3g每日2次,环丙氟哌酸0.4g每日2次治疗,疗程14天。5组的治愈率分别为33.3％、 25％、83.3％、100％和87.5％。30株仿寒杆菌时氟霉素敏感率为10％,氨苄青霉素为20％,氟嗪酸96.7％(MIC_(90)为1μg/ml),氟哌酸、甲氟哌酸及环丙氟哌酸均为100％(MIC_(90)分别为2μg/ml、1μg/ml及0.25μg/ml)。
42 cases of menstrual blood or bone marrow cultures confirmed typhoid fever were randomly divided into 5 groups. Control group intravenous ampicillin, daily 5 ~ 6g, and gentamicin plus 16 ~ 240,000 U daily treatment of 14 to 21 days. The four groups were treated with norfloxacin 0.3 ~ 0.4g three times a day, cilofloxacin 0.4g twice daily, triflumuron 0.3g twice daily, ciprofloxacin 0.4g twice daily Treatment, treatment 14 days. The cure rates in the 5 groups were 33.3%, 25%, 83.3%, 100% and 87.5%, respectively. 30 strains of Mycobacterium thermophila sensitive rate of 10%, ampicillin 20%, ofloxacin 96.7% (MIC_ (90) of 1μg / ml), norfloxacin, mefloxacin and ciprofloxacin The acid was 100% (MIC_ (90) 2 μg / ml, 1 μg / ml and 0.25 μg / ml, respectively).