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CD24在多种肿瘤细胞中大量表达,为乳腺癌中分离出乳腺癌干细胞(CD44/CD24LOW/-)标志物之一,笔者主要就CD24与肿瘤细胞增殖、生长、凋亡和转移侵袭的关系,以及该基因在肿瘤中的表达和与乳腺癌干细胞及乳腺癌关系等方面作一综述。
CD24 is abundantly expressed in a variety of tumor cells and is one of the markers for the isolation of breast cancer stem cells (CD44 / CD24LOW / -) in breast cancer. The author mainly discusses the relationship between CD24 and tumor cell proliferation, growth, apoptosis and metastasis, As well as the gene expression in the tumor and its relationship with breast cancer stem cells and breast cancer.