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应用放射免疫分析法对１６７例急性脑血管病（ＡＣＶＤ）患者血清泌乳素（ＰＲＬ）、生长激素（ＧＨ）、皮质醇（Ｆ）及血浆促肾上腺皮质激素（ＡＣＴＨ）水平变化进行了观察。结果发现：ＡＣＶＤ患者ＰＲＬ、ＧＨ、ＡＣＴＨ与Ｆ水平均显著高于对照组，ＡＣＶＤ并多器官功能衰竭（ＭＤＦ）患者４种激素水平显著高于ＡＣＶＤ各疾病组，随ＡＣＶＤ病程不同，４种激素水平也相应改变，１周时水平最高，２周后逐渐恢复、ＡＣＶＤ并ＭＤＦ重型患者（ＭＤＦ积分＞４分）ＰＲＬ、ＧＨ与Ｆ水平显著高于轻型患者（ＭＤＦ积分≤４分）。结果提示ＰＲＬ、ＧＨ和Ｆ可能参与了ＡＣＶＤ并ＭＤＦ的病理生理过程。
Serum prolactin (PRL), growth hormone (GH), cortisol (F), and plasma adrenocorticotropic hormone (ACTH) levels were measured by radioimmunoassay in 167 patients with acute cerebrovascular disease (ACVD). The results showed that the levels of PRL, GH, ACTH and F in ACVD patients were significantly higher than those in control group. The levels of four hormones in patients with ACVD and multiple organ failure (MDF) were significantly higher than those in ACVD patients. The levels of PRL, GH and F were significantly higher in patients with ACVD and MDF (MDF score> 4) than in those with light (MDF score ≤4). The results suggest that PRL, GH and F may be involved in the pathophysiology of ACVD and MDF.