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目的 :血管外膜参与血管重塑的病变基础是细胞表型转化 ,其显著特征之一是外膜成纤维细胞 (ＡＦ)被迅速激活并转化为肌成纤维细胞 (ＭＦ) ,后者兼有ＡＦ及平滑肌细胞的双重功能特性 ,增生并迁移至中膜及内膜。本研究应用差别显示聚合酶链反应 (ＤＤ -ＰＣＲ)技术筛选 2种表型细
OBJECTIVE: One of the salient features of vascular adventitial involvement in vascular remodeling is the phenotypic transformation of cells. One of the most striking features is the rapid activation of adventitial fibroblasts (AF) and the conversion to myofibroblasts (MF), both of which The dual functional properties of AF and smooth muscle cells proliferate and migrate to the media and intima. In this study, differential display polymerase chain reaction (DD-PCR) screening of two kinds of phenotypic fine