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带状疱疹是水痘-带状疱疹病毒(Varicella-Zoster Virus,VZV)再感染的一种类型,常见于系统性红斑狼疮(SLE)病人,已证实 SLE 病人血清中抗 VZV 抗体水平明显高于正常人,本文目的是阐明 SLE 病人抗 VZV 抗体升高的机理。病人和方法作者采用敏感的 ELISA 法代替补体结合中和试验,检测71例 SLE 病人(平均年龄35岁)、15例风湿性关节炎病人(平均年龄53岁)和20名正常人(平均年龄32岁)的血清抗 VZV 抗体,在 SLE 病人中,32例曾患带状疱疹,而风湿性关节炎病人和正常对照者均未
Shingles are a type of re-infection of Varicella-Zoster Virus (VZV), common in patients with systemic lupus erythematosus (SLE) and have demonstrated significantly higher serum levels of anti-VZV antibodies in SLE patients than in normal The purpose of this paper is to elucidate the mechanism of anti-VZV antibody elevation in SLE patients. Patients and Methods The authors used a sensitive ELISA assay instead of the complement neutralization test to test 71 SLE patients (mean age 35 years), 15 rheumatoid arthritis patients (mean age 53 years) and 20 normal subjects (mean age 32 Year) serum anti-VZV antibody in SLE patients, 32 patients had had herpes zoster, and rheumatoid arthritis patients and normal controls were not