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在发展中国家,结核是一种影响健康的严重疾病,BCG的接种在预防该病中起了重要作用,但对不同时间接种的作用认识不一,本文前瞻性的对照研究,比较了出生后不同时间接种BCG的结果,观察了接种菌苗的反应,BCG斑及其并发症的差别。对象和方法:选择足月生,身体健康,体重2500g的婴儿;排除其家庭有结核病史和密切接触史的婴儿。随机将婴儿分成2组,第1组为400名,于出生后3天内在左肩皮下接种BCG(0.05mg/0.05ml);第2组400名同上,于出生后第3个月(90±3天)接种,该组在接种前,进行精制蛋白质衍生物(PPD)试验:
In developing countries, tuberculosis is a serious health-affecting disease. Vaccinations with BCG play an important role in preventing the disease, but the effects of vaccination at different times are not understood. This prospective, controlled study, comparing postnatal The results of inoculation of BCG at different times were observed differences in response to vaccination vaccine, BCG plaque and its complications. Subjects and methods: Select full-term health, healthy, weighing 2500g infants; exclude their families have a history of tuberculosis and close contact with the history of infants. The infants were randomly divided into two groups: group 1, 400, subcutaneously with BCG (0.05 mg / 0.05 ml) on the left shoulder within 3 days of birth; group 2, 400 as above, and at 3 months after birth (90 ± 3 Day), the group was subjected to a purified protein derivative (PPD) test before inoculation: