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目的:评价白蛋白与蓝光照射联合治疗新生儿黄疸的临床指标,探讨其临床疗效。方法:选择2013年8月至2015年7月重庆市江津区中心医院收治的130例新生儿黄疸患儿,采取随机数表法分为对照组和观察组各65例,对照组给予茵栀黄与蓝光照射联合治疗,观察组给予白蛋白与蓝光联合治疗,统计并比较两组患者治疗前后的血清总胆红素(TBIL)、结合胆红素(DBIL)、非结合胆红素(IBIL)临床指标以及治疗有效率、不良反应率等。结果:在临床指标上,两组患者治疗后的各项胆红素指标均低于治疗前,但观察组显著优于对照组,差异具有统计学意义(P<0.05);总有效率观察组显著高于对照组,差异具有统计学意义(P<0.05);不良反应率观察组与对照组比较,差异均无统计学意义(P>0.05)。结论:白蛋白与蓝光照射联合治疗的方法,可以显著改善新生儿黄疸患儿的胆红素指标,能够有效提高治疗效果,不良反应较少,是一种安全、高效的治疗方法。
Objective: To evaluate the clinical indicators of neonatal jaundice combined with albumin and blue light irradiation to explore its clinical efficacy. Methods: From January 2013 to July 2015, 130 cases of neonatal jaundice in Jiangjin Central Hospital of Chongqing were enrolled. A random number table was used to divide the patients into 65 cases in the control group and observation group. The control group was given Yinzhihuang Combined with blue light irradiation, the observation group was treated with albumin and blue light. The levels of total bilirubin (TBIL), the combined bilirubin (DBIL), unconjugated bilirubin (IBIL) Clinical indicators and treatment efficiency, adverse reaction rates. Results: The indexes of bilirubin after treatment in both groups were lower than those before treatment, but the observation group was significantly better than the control group, the difference was statistically significant (P <0.05); the total effective rate observation group The difference was statistically significant (P <0.05). There was no significant difference in adverse reaction rate between the observation group and the control group (P> 0.05). Conclusion: The combined treatment of albumin and blue light can significantly improve neonatal jaundice in children with bilirubin index, which can effectively improve the treatment effect, with fewer adverse reactions, is a safe and efficient treatment.