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临床上早有报道,消化道异常(包括各种疾病和机械性、化学性过度刺激)可加重冠心病患者病情,饱餐和饮酒可诱发心绞痛。但其作用机理尚不清楚。本文分别以充气扩张胃和酒精灌胃的刺激方法,观察对冠脉血流的影响,并初步探讨其机理。方法选用健康杂种犬15条,麻醉开胸后行正压人工呼吸,沿左心耳基底部分离冠状动脉左旋支并安放电磁流量计探头(MF—27型)测左旋支血流量(CBF)。由颈部切开食管将一端
Clinically reported early, abnormal gastrointestinal (including various diseases and mechanical, chemical over-stimulation) can aggravate coronary heart disease patients, full meal and alcohol can induce angina. However, its mechanism of action is not clear. This article, respectively, to expand the gastric and alcohol gavage inflation method to observe the impact on coronary blood flow, and to explore its mechanism. Methods Fifteen healthy mongrel dogs were selected. Anesthetized with thoracotomy, positive pressure artificial respiration was performed. The left circumflex coronary artery was separated along the left atrial appendage and the left ventricular blood flow (CBF) was measured with a magnetic flowmeter (MF-27). The esophagus is cut by the neck to one end